RESUMO
Vertebral lesions have been the main evidence for infection by the Mycobacterium tuberculosis complex (MTC) in paleopathology. Skeletal involvement is expected in a small percentage of infected individuals. Recently, several authors report a correlation between rib lesions and tuberculosis (TB) complex infection. This study tests the hypothesis that rib lesions can serve as a useful marker for MTC infection within the Mississippian Schild skeletal collection from West-Central Illinois. Ribs from 221 adults and juveniles were examined, and affected individuals were tested for TB complex infection. DNA from rib samples of affected individuals was amplified with primers targeting the IS6110 insertion element, which is common to all members of the TB complex. Although it cannot allow discrimination between different species of TB, IS6110 is present in many copies within their genomes, and its presence is thus an indication of MTC infection. The results support the use of rib lesions as a marker for TB infection. Additionally, we demonstrate that MTC DNA can be recovered from ribs that lack lesions in individuals who have lesions of other bones. We recommend that an examination of ribs be incorporated into investigations for TB.
Assuntos
Adulto , Feminino , História Antiga , Humanos , Masculino , Pessoa de Meia-Idade , DNA Bacteriano/genética , Mycobacterium tuberculosis/genética , Costelas/lesões , Tuberculose Pulmonar/história , Elementos de DNA Transponíveis/genética , DNA Bacteriano/química , Illinois , Paleopatologia , Reação em Cadeia da Polimerase , Costelas/patologia , Tuberculose Pulmonar/patologiaRESUMO
35 cases of blunt cardiac trauma following vehicular accidents brought for autopsy to the morgue of Regional Institute of Medical Sciences, Imphal have been studied to find out types of cardiac injuries, their association with sternal and rib fractures, mechanism of causation, risk factors, etc. It was observed that 48.57% of the cases with blunt cardiac trauma had associated sternal and rib fractures. Maximum number (60%) of the cardiac rupture was seen in run-over cases. 40% of the cases had injury to the right ventricle. All the injuries were located on the anterior surface of the heart. In one (2.86%) case, laceration of the right atrium without any external injury of the chest region was observed. In assessing blunt cardiac trauma victims in vehicular accidents, knowledge about the commonest sites, types and degrees of injuries as has been highlighted in the present study will be of great help in a timely intervention.
Assuntos
Acidentes de Trânsito/complicações , Acidentes de Trânsito/mortalidade , Autopsia , Coração/lesões , Humanos , Índia , Fraturas das Costelas/etiologia , Costelas/lesões , Esterno/lesões , Ferimentos não Penetrantes/etiologia , Ferimentos não Penetrantes/mortalidade , Ferimentos não Penetrantes/estatística & dados numéricosRESUMO
El síndrome consiste en la subluxación del extremo distal de la 8a. y'o 10a. costillas generalmente secundario y traumatismo. Se manifiesta principalmente por el dolor abdominal alto, lo cual hace se confunda con patología visceral. El diagnóstico es clínico y debiera tenerse presente como diagnóstico diferencial evitando así múltiples exploraciones a los pacientes que lo sufren